Frequently Asked Questions

Why have I been told that I should not take progesterone if I had a hysterectomy?

Because synthetic progestins (Provera) have a negative impact on the body, they are not recommended unless absolutely necessary (as to protect against uterine cancer). Unopposed estrogen (without progesterone) does have significant risks including: increasing the risk of blood clots, fluid retention, promoting fat synthesis and increasing the risk of breast cancer. Progesterone, as opposed to synthetic progestins, has beneficial effects as listed above, including a decreased risk of breast cancer. There are progesterone receptors in all tissues of the body, and it has beneficial effects on these tissues, which include the heart, the bones and the brain. Natural progesterone should always be given along with estrogen replacement.


Should I take hormonal replacement therapy?

If so, what type? For most women, with the right hormones, the benefits outweigh any risks. In most cases, whether you have had a hysterectomy or not, your estrogen and progesterone levels should be optimized with replacement therapy. The estrogen replacement should contain a combination of transdermal estradiol for maximal benefit, estriol for protection against breast cancer, and natural progesterone to balance the estrogen and for its added benefits, which includes reversal of osteoporosis, and additional protection against breast cancer. The addition of a small amount of testosterone can usually add benefits, as well, including increased sex drive, feelings of well-being and reversal of osteoporosis.


I take Premarin, is it OK?

Premarin, especially when given orally, can increase the risk of sroke, heart attack, and breast cancer. This is especially true if a synthetic progestin is added. Natural estrogen with a combination of estradiol and estriol with natural progesterone is a much better choice.


Why aren’t the superior natural hormones promoted more?

They are very popular in Europe and are becoming more popular as more American women learn about the advantages. Because no patent protection can be granted for these natural hormones in the US, no drug company can expect large profits from the sale. Thus, with little financial incentive, no major drug company produces or promotes them.